The introduction of 'No jab, No school' policy and the refinement of measles immunisation strategies in high-income countries

BMC MEDICINE, 2019
Trentini Filippo; Poletti Piero; Melegaro Alessia; Merler Stefano
Abstract

We simulated the evolution of measles immunity profiles in seven distinct countries for the period 2018-2050 and evaluated the effect of possible adjustments of immunisation strategies adopted in the past on the overall fraction and age distribution of susceptible individuals in different high-income demographic settings. The proposed model accounts for country-specific demographic components, current immunity gaps and immunisation activities in 2018. Vaccination strategies considered include the enhancement of coverage for routine programmes already in place and the introduction of a compulsory vaccination at primary school entry in countries where universal school enrolment is likely achieved.